Cushing's Disease

With a five multiplication greater chance for women to be diagnosed over men, Hypercortisolism or Cushings sickness occurs in an estimated disco music biscuit to 15 one million million people per year amid the ages of twenty dollar notification to fifty (Cushings Disease). Out of those ten to fifteen million people closely ten percent of those cases be children (Keil). Discovered by Dr. Harvey Cushing in 1932, this malady is caused by an overrun of the hormone ACTH in the hypophysis gland contumacious behind the optic nerves, at the base of the whiz. This over output signal produces a tumour on the pituitary gland, which can cause a smorgasbord of symptoms for the patient. These symptoms can drastically change the patients mood and appearance (Margulies) In 1912, Dr. Harvey Williams Cushing was born in Cleveland, Ohio and was improve through Johns Hopkins, Yale and Harvard Universities. He was neurosurgeon and taught medicine at Harvard from 1912 to 1932, when he then became a professor at Yale. His specialty was the understanding and the pituitary gland. Patients were sent to Cushing from all over and by 1931, he had performed more(prenominal) than 2000 tumor operations (Brennan and Clarage). Cushing disease is the ready given to a precise type of Cushings syndrome caused by too a upright deal ACTH production in the pituitary gland.

The tumor, or adenoma, secretes enlarged amounts of ACTH which causes the adrenal glands to overproduce the steroid called cortisol. This disease was draw by Harvey Cushing in 1932. It is in addition called Itsenko-Cushing Syndrome, hyperadrenocorticism or hypercortisolism. Cushings can also be found in dogs, horses and sometimes, still rarely, in cats (Feldman and Gilkers). at that place are a good(a) variety of both personal and emotional symptoms for the disease. Some of the natural symptoms entangle; upper remains obesity with thin implements of war/legs, a round, red full typeface or daydream face. More include; slower growth in children, devoted to acne or otherwise skin infections, stretch tag (also called straie), thinning...If you deprivation to get a full essay, order it on our website: Orderessay

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